Diffusion and dissolution models for drug-delivery systems
2015-03-24
Sean McGinty - University of Strathclyde, Glasgow, UK
The study of drug/device combinations for controlled drug release has gained significant momentum in recent years and is responsible for considerable global research budgets across academia and Industry. In this talk, I will discuss my group’s research in this area which includes modelling drug release from polymer-coated and nanoporous drug delivery devices, coupling drug release with tissue absorption, and parameter estimation methods. The mechanisms of drug release typically include diffusion, dissolution and in some cases a combination of both. Within the tissue, convection, diffusion and reaction typically occur simultaneously. We adopt a three-pronged approach to tackle these problems, making use of analytical, numerical and experimental techniques.
