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Comics&Science - Archimede 2.0

AUTORI: ROBERTO NATALINI,

Il 1 Novembre nell'ambito di Lucca Comics&Science, verrà presentato il nuovo albo Comics&Science, contenente tra l'altro una storia a fumetti di Giuseppe Palumbo sul manoscritto perduto di Archimede

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Multi-omic Data Integration

AUTORI: PAOLO TIERI,

Stable, predictive biomarkers and interpretable disease signatures are seen as a significant step towards personalized medicine. In this perspective, integration of multi-omic data coming from genomics, transcriptomics, glycomics, proteomics, metabolomics is a powerful strategy to reconstruct and analyse complex multi-dimensional interactions, enabling deeper mechanistic and medical insight. At the same time, there is a rising concern that much of such different omic data –although often publicly and freely available- lie in databases and repositories underutilised or not used at all. Issues coming from lack of standardisation and shared biological identities are also well-known. From these considerations, a novel, pressing request arises from the life sciences to design methodologies and approaches that allow for these data to be interpreted as a whole, i.e. as intertwined molecular signatures containing genes, proteins, mRNAs and miRNAs, able to capture inter-layers connections and complexity. This book collects papers discussing data integration approaches and methods of several types and extents, their application in understanding the pathogenesis of specific diseases or in identifying candidate biomarkers to exploit the full benefit of multi-omic datasets and their intrinsic information content.

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RETI - concetti essenziali e idee di base

AUTORI: PAOLO TIERI,

Traduzione italiana di NETWORK LITERACY - essential concepts and core ideas, un agile opuscolo destinato al pubblico che rappresenta il distillato dei pensieri, commenti e scritti di oltre 30 ricercatori di scienze delle reti, educatori, insegnanti e studenti.

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